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  4. SF-1 antagonist-1

SF-1 antagonist-1 (compound 11) 是 SF-1 的拮抗剂。SF-1 antagonist-1 影响 SF-1 的转录活性，EC50 值 ＜200 nM。SF-1 antagonist-1 抑制大鼠间质肿瘤细胞的增殖。SF-1 antagonist-1 可用于癌症的研究。

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SF-1 antagonist-1 Chemical Structure

SF-1 antagonist-1 Chemical Structure

CAS No. : 2842079-86-9

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SF-1 antagonist-1 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

SF-1 antagonist-1 (compound 11) is a antagonist of steroidogenic factor 1 (SF-1). SF-1 antagonist-1 affects SF-1 transcriptional activity with an EC50 value of ＜200 nM. SF-1 antagonist-1 inhibits the proliferation of Rat Leydig tumor cells. SF-1 antagonist-1 can be used for the research of cancer[1].

体外研究
(In Vitro)

SF-1 antagonist-1 (0-20 μM) affects SF-1 transcriptional activity with an EC50 value of ＜200 nM[1].
SF-1 antagonist-1 (0-20 μM; 48 h) affects proliferation of R2C cells[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

SF-1 antagonist-1 相关抗体:

Cell Proliferation Assay[1]

Cell Line: Rat Leydig tumor cell line, R2C
Concentration: 0-20 μM
Incubation Time: 48 h
Result: Inhibited proliferation of R2C cells with an EC50 value of ＜200 nM.
分子量

490.41

Formula

C22H18F4N6O3
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

SF-1 antagonist-1 相关分类

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

SF-1 antagonist-12842079-86-9Otherspyrazolopyrimidinone derivativepreparationanti-proliferationR2CInhibitorinhibitorinhibit

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SF-1 antagonist-1
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