1. JAK/STAT Signaling Autophagy Apoptosis
  2. Autophagy Pim Apoptosis
  3. SGI-1776

SGI-1776 是 Pim kinases 的抑制剂,抑制 Pim-1,Pim-2 和 Pim-3 的活性,IC50 值分别为 7 nM,363 nM 和 69 nM。

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SGI-1776 Chemical Structure

SGI-1776 Chemical Structure

CAS No. : 1173928-26-1

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    SGI-1776 purchased from MCE. Usage Cited in: Cell Death Dis. 2018 Feb 22;9(3):307.  [Abstract]

    PIM1 directly phosphorylated Smad2 and Smad3 and that inhibition of PIM1 kinase activity with SGI-1776 significantly reduces the protein levels of p-Smad2 and p-Smad3

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    产品名称:
    SGI-1776
    目录号:
    HY-13287A
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