1. Signaling Pathways
  2. JAK/STAT Signaling
  3. Pim
  4. Pim Inhibitors

Pim Inhibitors

PIM1

PIM2

PIM3

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Sorry. There is currently no product that acts on isoform together.

Please try each isoform separately.

Pim Inhibitors
Product Name PIM1 PIM2 PIM3 Purity
AZD1208  
PIM2
  99.71%
CRT0066101 dihydrochloride  
PIM2, IC50: 135.7 nM
  99.92%
PIM-447 dihydrochloride
PIM1
PIM2
PIM3
99.94%
AZD1897
PIM1, IC50: <3 nM
PIM2, IC50: <3 nM
PIM3, IC50: <3 nM
Pim-1 kinase inhibitor 11
PIM1, IC50: 0.18 μM
   
Pim1/AKK1-IN-1
PIM1
    98.20%
Quercetagetin
PIM1, IC50: 0.34 μM
PIM2, IC50: 3.45 μM
  99.94%
SMI-4a
PIM1, IC50: 24 μM
PIM1, Ki: 0.6 μM
PIM2, IC50: 100 μM
  99.63%
GDC-0339
PIM1
PIM2
PIM3
99.87%
SMI-16a
PIM1
PIM2
  ≥98.0%
Uzansertib phosphate
PIM1, IC50: 0.24 nM
PIM2, IC50: 30 nM
PIM3, IC50: 0.12 nM
99.39%
CK2/ERK8-IN-1
PIM1, Ki: 8.65 μM
    ≥99.0%
SEL24-B489
PIM1, Kd: 2 nM
PIM2, Kd: 2 nM
PIM3, Kd: 3 nM
99.02%
TCS PIM-1 1
PIM1, IC50: 50 nM
    98.01%
CRT0066101  
PIM2, IC50: 135.7 nM
 
PIM1-IN-1
PIM1, IC50: 7 nM
PIM2, IC50: 5530 nM
PIM3, IC50: 70 nM
99.83%
HTH-01-091
PIM1, IC50: 60.6 nM
    98.64%
PIM1-IN-2
PIM1, Ki: 91 nM
    ≥99.0%
Uzansertib
PIM1, IC50: 0.24 nM
PIM2, IC50: 30 nM
PIM3, IC50: 0.12 nM
PIM3-IN-1 hydrochloride  
PIM2
PIM3
GSK-3β inhibitor 13
PIM1, IC50: 0.38 μM
   
PIM1-IN-4
PIM1
   
CK2/PIM1-IN-1
PIM1, IC50: 4.327 μM
   
CDK6/PIM1-IN-1
PIM1, IC50: 88 nM
PIM2, IC50: >10 μM
PIM3, IC50: 92 nM
PIM1-IN-7
PIM1, IC50: 0.67 μM
   
PIM-IN-2  
PIM2
 
Pim-1 kinase inhibitor 9
PIM1, IC50: 0.24 μM
PIM2, IC50: 10.53 μM
 
PIM1-IN-6
PIM1, IC50: 0.60 μM
   
PIM-1/HDAC-IN-1
PIM1, IC50: 343.87 ± 1 nM
   
Multi-kinase-IN-6
PIM1, IC50: 0.42 μM
   
PIM-1/CK2-IN-2
PIM1
   
CRT0066101 trihydrochloride  
PIM2, IC50: 135.7 nM
 
PIM1-IN-3
PIM1
   
HS56
PIM1, Ki: 2.94 μM
PIM2, Ki: >100 μM
PIM3, Ki: 0.208 μM
Pim-1 kinase inhibitor 3
PIM1, IC50: 35.13 nM
   
Pim-1/2 kinase inhibitor 2
PIM1, IC50: 1.31 μM
PIM2, IC50: 0.67 μM
 
GNE-955
PIM1, Ki: 0.018 nM
PIM2, Ki: 0.11 nM
PIM3, Ki: 0.08 nM