2. JAK/STAT Signaling
  3. Pim
  4. PIM1-IN-7

PIM1-IN-7 (compound 6c) 是一种有效的 PIM-1 抑制剂，其 IC50 为 0.60 μM。PIM1-IN-7 对 HCT-116 和 MCF-7 细胞表现出较高的细胞毒性活性，IC50 分别为42.9 和7.68 μM。

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PIM1-IN-7 Chemical Structure

PIM1-IN-7 Chemical Structure

CAS No. : 2439168-72-4

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PIM1-IN-7 相关抗体

Top Publications Citing Use of Products

查看 Pim 亚型特异性产品:

查看所有亚型
PIM1 PIM2 PIM3

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

PIM1-IN-7 (compound 6c) is a potent PIM-1 inhibitor, with an IC50 of 0.67 μM. PIM1-IN-7 shows the high cytotoxicity activity against HCT-116 and MCF-7 cells, with IC50 values of 42.9 and 7.68 μM, respectively[1].

IC50 & Target

PIM1

0.67 μM (IC50)

分子量

385.46

Formula

C23H23N5O
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

PIM1-IN-7 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PIM1-IN-72439168-72-4PimPim kinasesPyrazolo[1,5-a]pyrimidineAntitumor activityHCT-116MCF-7Inhibitorinhibitorinhibit

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