2. Membrane Transporter/Ion Channel
  3. GLUT
  4. SLC26A3-IN-1

SLC26A3-IN-1 是一种阴离子交换蛋白 SLC26A3 的抑制剂 (IC50=340 nM)。SLC26A3 属于溶质载体 (SLC) 蛋白，属于 SLC26 家族。SLC26 家族对氯化物、碳酸氢盐、硫酸盐和草酸盐具有广泛的阴离子特异性。SLC26A3 在腺瘤 (DRA) 中下调，参与氯化物和草酸盐的肠道吸收。SLC26A3 功能突变的丧失与氯离子丢失性腹泻有关。

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SLC26A3-IN-1 Chemical Structure

SLC26A3-IN-1 Chemical Structure

CAS No. : 307552-53-0

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规格 价格 是否有货 数量
1 mg ￥2240
1 - 2 周
5 mg ￥4998
1 - 2 周
10 mg 现货 1 - 2 周
50 mg   询价  
100 mg   询价  

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SLC26A3-IN-1 相关抗体

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

SLC26A3-IN-1 is an inhibitor of anion exchanger protein SLC26A3 (IC50=340 nM). SLC26A3 belongs to solute carrier (SLC) proteins, and the SLC26 family. SLC26 family has broad anion specificity for chloride, bicarbonate, sulfate and oxalate. SLC26A3 down-regulates in adenoma, DRA, involves in in intestinal absorption of chloride and oxalate. The loss of SLC26A3 function mutations is associated with chloride-losing diarrhea[1].

体外研究
(In Vitro)

SLC26A3-IN-1 (化合物4a) (10 μM; 10 min) 对 SLC26A3 的抑制率为 87%[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

SLC26A3-IN-1 相关抗体:
分子量

358.39

Formula

C23H18O4
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

SLC26A3-IN-1 相关分类

  • 摩尔计算器

  • 稀释计算器

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

SLC26A3-IN-1307552-53-0GLUTGlucose transporterSLC26A3chloride-losing diarrheaInhibitorinhibitorinhibit

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