2. JAK/STAT Signaling Stem Cell/Wnt TGF-beta/Smad Immunology/Inflammation
  3. STAT TGF-beta/Smad Interleukin Related
  4. Smad2/3-IN-1

Smad2/3-IN-2 (Compound 27) 是 TGF-β依赖性 Smad2/3 和IL -4 依赖性 STAT6 信号通路的抑制剂，IC50 分别为 90 nM 和 20 nM。

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Smad2/3-IN-1 Chemical Structure

Smad2/3-IN-1 Chemical Structure

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 是否有货
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Customer Review

Smad2/3-IN-1 相关抗体

Top Publications Citing Use of Products

查看 STAT 亚型特异性产品:

查看所有亚型
STAT3 STAT5 STAT6 STAT1

查看 Interleukin Related 亚型特异性产品:

查看所有亚型
IL-1 IL-2 IL-3 IL-4 IL-5 IL-6 IL-8 IL-10 IL-12 IL-13 IL-15 IL-17 IL-23 IL-7 IL-33 IL-22

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Smad2/3-IN-2 (Compound 27) is an inhibitor for TGF-β-dependent Smad2/3 and IL-4-dependent STAT6 signaling pathway, with IC50s of 90 and 20 nM, respectively[1].

IC50 & Target

IL-4

20 nM (IC50)

Smad2/3

90 nM (IC50)

分子量

368.81

Formula

C18H21ClO6
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Smad2/3-IN-1 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Smad2/3-IN-1STATTGF-beta/SmadInterleukin RelatedTransforming growth factor betaILHepG2antifibroticInhibitorinhibitorinhibit

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产品名称：
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目录号：
HY-162405
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