1. 多肽产品
  2. 多肽及其衍生物
  3. 抑制剂与底物肽
  4. smMLCK peptide

smMLCK peptide  (Synonyms: Smooth-Muscle Myosin Light-Chain Kinase (796-815))

目录号: HY-P10346
产品使用指南

smMLCK peptide 是平滑肌肌球蛋白轻链激酶 (smMLCK) 的特异性抑制剂。smMLCK peptide 肽通过模拟底物并竞争性地抑制实际底物与酶的结合,从而抑制激酶活性。这种抑制作用防止了肌球蛋白轻链的磷酸化,从而抑制了肌肉收缩。

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Custom Peptide Synthesis

smMLCK peptide Chemical Structure

smMLCK peptide Chemical Structure

CAS No. : 172960-20-2

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

smMLCK peptide is a specific inhibitor of smooth muscle myosin light chain kinase (smMLCK). The smMLCK peptide mimics the substrate and competitively inhibits the binding of the actual substrate to the enzyme, thereby inhibiting the kinase activity. This inhibition prevents the phosphorylation of the myosin light chain, thus inhibiting muscle contraction[1].

分子量

2278.62

Formula

C98H168N38O25

CAS 号
Sequence

Ala-Arg-Arg-Lys-Trp-Gln-Lys-Thr-Gly-His-Ala-Val-Arg-Ala-Ile-Gly-Arg-Leu-Ser-Ser

Sequence Shortening

ARRKWQKTGHAVRAIGRLSS

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
smMLCK peptide
目录号:
HY-P10346
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