2. 多肽产品
  3. 多肽及其衍生物
  4. 抑制剂与底物肽
  5. sPLA2-IIA Inhibitor

sPLA2-IIA Inhibitor 是 FLSYK 的环状五肽类似物（环2-Nal-Leu-Ser-2-Nal-Arg (c2)），与 hGIIA（人类 IIA 磷脂酶 A2）结合并抑制其水解能力。sPLA2 是酯酶超家族的成员，可催化甘油磷脂 sn-2 位上的酯键水解，释放游离脂肪酸，例如花生四烯酸和溶血磷脂。

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Custom Peptide Synthesis

sPLA2-IIA Inhibitor Chemical Structure

sPLA2-IIA Inhibitor Chemical Structure

CAS No. : 236394-37-9

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sPLA2-IIA Inhibitor 相关抗体

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

sPLA2-IIA Inhibitor is a cyclic pentapeptide analog of FLSYK (cyclic 2-Nal-Leu-Ser-2-Nal-Arg (c2)), that binds to hGIIA (human IIA phospholipase A2) and inhibits its hydrolytic ability. sPLA2 is a member of the esterase superfamily that catalyzes the hydrolysis of the ester bond at the sn-2 position of glycerophospholipids, releasing free fatty acids such as arachidonic acid and lysophospholipids[1].

分子量

750.89

Formula

C41H50N8O6
CAS 号
Sequence

Cyclo({Nal}-Leu-Ser-{Nal}-Arg)
Sequence Shortening

Cyclo({Nal}-LS-{Nal}-R)
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

sPLA2-IIA Inhibitor 相关分类

  • 摩尔计算器

  • 稀释计算器

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

sPLA2-IIA Inhibitor236394-37-9OthersGroup IIA phospholipase A2FLSYK inhibitorbinding sitevimentinmolecular dynamicsprotein-protein interactiondockingInhibitorinhibitorinhibit

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