Phospholipase Inhibitors

Phospholipase A

PLD

Phospholipase C

Phospholipase Inhibitors & Antagonists

Product Name	Phospholipase A	PLD	Phospholipase C	Purity
sPLA2 inhibitor 2	sPLA2, IC₅₀: 0.0475 μM
Varespladib	sPLA2, IC₅₀: 9 nM			99.94%
Pyrrophenone	cPLA2α, IC₅₀: 4.2 nM			99.76%
Bromoenol lactone	PLA2, IC₅₀: 7 μM			98.41%
1-Naphthaleneacetic acid	PLA2, IC₅₀: 13.16 μM			99.89%
VU0155069		PLD1, IC₅₀: 46 nM PLD2, IC₅₀: 933 nM		98.55%
VU0359595		PLD1, IC₅₀: 3.7 nM PLD2, IC₅₀: 6.4 μM		99.65%
OBAA	PLA2, IC₅₀: 70 nM			99.27%
Halopemide		PLD1, IC₅₀: 220 nM PLD2, IC₅₀: 310 nM		99.65%
PACOCF3	PLA2, IC₅₀: 3.8 μM			≥98.0%
sPLA2 inhibitor 1	sPLA2, IC₅₀: 29 nM			99.47%
(S)-Bromoenol lactone	PLA2			≥99.0%
Rapanone	PLA2, IC₅₀: 2.6 μM			99.20%
CAY10502	cPLA2α, IC₅₀: 4.3 nM			≥99.0%
VU533		PLD1, EC₅₀: 0.3 μM		99.71%
Alminoprofen	sPLA2			99.91%
trans-Benzylideneacetone	PLA2			99.29%
SB-435495	Lp-PLA2, IC₅₀: 0.06 nM			99.80%
1-Naphthaleneacetic acid potassium salt	PLA2, IC₅₀: 13.16 μM			99.64%
Giripladib	cPLA2α			99.68%
Varespladib sodium	sPLA2, IC₅₀: 9 nM			≥98.0%
A3373		PLD1, IC₅₀: 325 nM PLD2, IC₅₀: 15.15 μM		99.06%
CAY10590	sPLA2			≥98.0%
BML-280		PLD2 PLD1		99.64%
(Z)-Oleyloxyethyl phosphorylcholine	sPLA2
Lp-PLA2-IN-1	Lp-PLA2			99.18%
(2E)-OBAA	PLA2, IC₅₀: 70 nM
Lp-PLA2-IN-2	Lp-PLA2, IC₅₀: 120 nM
VI-60	cPLA₂
FKGK11	PLA2			99.00%
SB-435495 hydrochloride	Lp-PLA2, IC₅₀: 0.06 nM
Efipladib	cPLA2α, IC₅₀: 0.04 μM cPLA2α, Ki: 0.067 μM
Me-Indoxam	sPLA2
Protizinic acid	PLA2, IC₅₀: 210 μM
Scalaradial	sPLA2, IC₅₀: 70 nM
ASM-IN-2			PLC, IC₅₀: 0.87 μM
Lp-PLA2-IN-14	rhLp-PLA2, pIC₅₀: 8.4
SB-435495 ditartrate	Lp-PLA2, IC₅₀: 0.06 nM
YM-26734	sPLA2
VU0155069 hydrochloride		PLD1, IC₅₀: 46 nM
VU 0364739 hydrochloride		PLD2, IC₅₀: 20 nM PLD1, IC₅₀: 1500 nM
AX048	cPLA₂
Ochnaflavone	sPLA2, IC₅₀: 3.45 μM
LY 178002	PLA2, IC₅₀: 6.3 μM

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