1. Metabolic Enzyme/Protease
  2. Phospholipase
  3. VU0155069 hydrochloride

VU0155069 hydrochloride  (Synonyms: CAY10593 hydrochloride)

目录号: HY-108612A
产品使用指南

VU0155069 hydrochloride (CAY10593 hydrochloride) 是一种有效的选择性磷脂酶 D (PLD) 抑制剂,对 PLD1PLD2IC50 值分别为 46 和 933 nM。VU0155069 hydrochloride 可抑制人类和小鼠乳腺癌细胞系的迁移。

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VU0155069 hydrochloride Chemical Structure

VU0155069 hydrochloride Chemical Structure

CAS No. : 1781834-89-6

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VU0155069 hydrochloride 的其他形式现货产品:

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

VU0155069 hydrochloride (CAY10593 hydrochloride) is a potent selective phospholipase D (PLD) inhibitor. The IC50 values for PLD1 and PLD2 are 46 and 933 nM, respectively. VU0155069 hydrochloride inhibits migration of human and mouse breast cancer cell lines[1][2].

IC50 & Target

PLD1

46 nM (IC50)

体外研究
(In Vitro)

VU0155069 (0.5 μM, 1 h) 显著抑制 (R)-DOI (3 μM) 诱导的 MCF-7 细胞 [3H]PtdBut的产生[3]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

499.43

Formula

C26H28Cl2N4O2

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
VU0155069 hydrochloride
目录号:
HY-108612A
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