2. Cell Cycle/DNA Damage
  3. SRPK
  4. SRSF1-IN-1

SRSF1-IN-1 (STP2) 是一种 SRSF1 抑制剂，用过抑制 SRSF1 表达来调节 Bcl-x 前体 mRNA 的剪切。SRSF1-IN-1 在体内外均表现出抗肿瘤活性，对 HepG2、MCF7等肿瘤细胞的 IC50 为 0.33-6.93 μM。SRSF1-IN-1 在小鼠体内展示出良好的安全性，通过腹腔注射 1 g/kg 的 SRSF1-IN-1，不会导致小鼠死亡或病理损伤。SRSF1-IN-1 有望用于抗肿瘤领域的研究[1]。

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SRSF1-IN-1 Chemical Structure

SRSF1-IN-1 Chemical Structure

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

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SRSF1-IN-1 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

SRSF1-IN-1 (STP2) is a SRSF1 inhibitor that regulates the splicing of Bcl-x precursor mRNA by inhibiting SRSF1 expression. SRSF1-IN-1 exhibits anti-tumor activity both in vitro and in vivo, with IC50 values ranging from 0.33 to 6.93 μM against tumor cells such as HepG2 and MCF7. In mice, SRSF1-IN-1 demonstrates good safety, as intraperitoneal injection at 1 g/kg does not cause death or pathological damage. SRSF1-IN-1 holds promising potential for research in the field of anti-tumor therapy[1].

分子量

376.47

Formula

C20H24O5S
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

SRSF1-IN-1 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

SRSF1-IN-1SRPKSerine-arginine protein kinasesInhibitorinhibitorinhibit

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目录号：
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