2. Cell Cycle/DNA Damage Epigenetics
  3. Sirtuin
  4. SRTCX1002

SRTCX1002 是一种有效的 SIRT1 激活剂 (STAC)，通过促进 p65 去乙酰化和抑制 NF-κB 活性来抑制炎症反应。SRTCX1002 抑制刺激诱导的 NF-κB 转录激活和 LPS 诱导的 TNFα 分泌，IC50 分别为 0.71 和 7.58 µM。

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SRTCX1002 Chemical Structure

SRTCX1002 Chemical Structure

CAS No. : 1203479-63-3

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SRTCX1002 相关抗体

Top Publications Citing Use of Products

查看 Sirtuin 亚型特异性产品:

查看所有亚型
Sirtuin SIRT1 SIRT2 SIRT3 SIRT6 SIRT5 SIRT7

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

SRTCX1002 is a potent activator of SIRT1 (STAC), suppresses inflammatory responses through promotion of p65 deacetylation and inhibition of NF-κB Activity. SRTCX1002 suppresses stimuli-induced NF-κB transcriptional activation and LPS-induced TNFα secretion with IC50s of 0.71 and 7.58 µM, respectively[1].

分子量

405.47

Formula

C21H19N5O2S
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

SRTCX1002 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

SRTCX10021203479-63-3SRTCX 1002SRTCX-1002SirtuinSIRT1 activatorSTACinflammatory responsesp65 deacetylationNF-κB ActivityInhibitorinhibitorinhibit

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