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  4. Streptavidin

Streptavidin  (Synonyms: 链霉亲和素)

目录号: HY-P3152 纯度: 98.40%
COA 产品使用指南

摩尔计算器

Streptavidin 是一种约 60 kDa 的同型四聚体。Streptavidin 高亲和力地结合四个生物素分子。生物素与 Streptavidin 的结合亲和力是迄今为止报道的最高非共价相互作用之一，KD 约为 0.01 pM。Streptavidin 具有免疫抑制作用。

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Streptavidin Chemical Structure

Streptavidin Chemical Structure

CAS No. : 9013-20-1

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规格 价格 是否有货 数量
1 mg ￥500
In-stock
5 mg ￥1600
In-stock
10 mg ￥2400
In-stock
50 mg   询价  
100 mg   询价  

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Customer Review

Streptavidin 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Streptavidin is a ∼60 kDa homotetramer. Streptavidin binds four molecules of biotin with the highest affinity. The binding affinity of biotin to streptavidin is one of the highest reported for a non-covalent interaction to date, with a KD ∼ 0.01 pM[1]. Streptavidin has an immunosuppressive role[2].

体外研究
(In Vitro)

Streptavidin (2-200 μg/mL) significantly suppresses the proliferation of Lewis T cells to WF by 76%-83% compared with untreated responders[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Streptavidin 相关抗体:

Cell Viability Assay[1]

Cell Line: Lewis T cells
Concentration: 2-200 μg/mL
Incubation Time:
Result: Inhibited the proliferation of Lewis T cells to WF stimulators by 76%-83% compared with untreated responders, lower concentrations of 0.1 and 0.2 μg/mL did not significantly inhibit T-cell proliferation.
体内研究
(In Vivo)

Streptavidin (8-80 mg/kg) treatment is effective in prolonging rat cardiac allografts in the high-responder WF-to-Lewis combination[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Lewis rats[2]
Dosage: 8, 12, 20, 40, 60, or 80 mg/kg
Administration: Administered IP for 5 consecutive days after transplantation was combined with a single dose of 0.5 mL antilymphocyte serum (ALS) on day 0
Result: Prolonged cardiac allograft survival from MST of 7.3±0.5 and 8.4±0.5 days in naive and ALS-treated controls, respectively, to 15±1, 20±3, 16±3, 17±3, and 23±2 days, respectively.
CAS 号
性状

固体

颜色

White to off-white

中文名称

链霉亲和素
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

溶解性数据
细胞实验： 

H2O 中的溶解度 : 100 mg/mL (超声助溶)

  • 摩尔计算器

  • 稀释计算器

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量
=
浓度
×
体积
×
分子量 *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start)

C1

×
体积 (start)

V1

=
浓度 (final)

C2

×
体积 (final)

V2

动物溶解方案计算器
请输入动物实验的基本信息：

给药剂量

mg/kg

动物的平均体重

g

每只动物的给药体积

μL

动物数量

只
由于实验过程有损耗，建议您多配一只动物的量
计算结果
工作液所需浓度 : mg/mL
该产品水溶性佳，请具体参考实测 水 / PBS / Saline 中的溶解度数据。
您所需的储备液浓度超过该产品的实测溶解度，如有需要，请与 MCE 中国技术支持联系。
纯度 & 产品资料

纯度: ≥99.0%

COA (281 KB)

产品使用指南 (1538 KB)
参考文献

Streptavidin 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Streptavidin9013-20-1链霉亲和素Biochemical Assay Reagentsbiotin-binding proteinversatile affinity tagvisualize biotinInhibitorinhibitorinhibit

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