2. Neuronal Signaling
  3. Amyloid-β
  4. Tabersonine hydrochloride

Tabersonine hydrochloride  (Synonyms: 水甘草碱盐酸盐)

目录号: HY-N1431A
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摩尔计算器

Tabersonine hydrochloride 是一种主要从蔷薇中分离出的吲哚类生物碱。Tabersonine 能破坏 Aβ(1-42) 的聚合和改善 Aβ 聚集诱导的细胞毒性。Tabersonine hydrochloride 具有抗炎活性，可用于 ALI/ARDS 的研究。

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Tabersonine hydrochloride Chemical Structure

Tabersonine hydrochloride Chemical Structure

CAS No. : 29479-00-3

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Other Forms of Tabersonine hydrochloride:

Tabersonine hydrochloride 相关抗体

Top Publications Citing Use of Products

MCE 顾客使用本产品发表的 1 篇科研文献

IHC

    Tabersonine hydrochloride purchased from MCE. Usage Cited in: Phytother Res. 2023 Feb 8.  [Abstract]

    Tabersonine (Tab; 20 mg/kg; i.v; every 2 days for 12 weeks) significantly reduces the expression and transcription of these fibrotic related biomarkers (mRNA levels of Col1a1, Tgfb1, and Acta2, protein levels of COL-1 and TGF-β) in C57BL/6 mice.

    • 生物活性

    • 纯度 & 产品资料

    • 参考文献

    生物活性

    Tabersonine hydrochloride is an indole alkaloid mainly isolated from Catharanthus roseus. Tabersonine disrupts Aβ(1-42) aggregation and ameliorates Aβ aggregate-induced cytotoxicity. Tabersonine has anti-inflammatory activities and is a potential therapeutic candidate for the treatment of ALI/ARDS[1].

    分子量

    372.89

    Formula

    C21H25ClN2O2
    CAS 号
    中文名称

    水甘草碱盐酸盐
    结构分类
    初始来源
    运输条件

    Room temperature in continental US; may vary elsewhere.
    储存方式

    Please store the product under the recommended conditions in the Certificate of Analysis.
    纯度 & 产品资料
    参考文献

    Tabersonine hydrochloride 相关分类

    • 摩尔计算器

    • 稀释计算器

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    • Do most proteins show cross-species activity?

      Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

    Keywords:

    Tabersonine29479-00-3水甘草碱盐酸盐Amyloid-ββ-amyloid peptideAβAbetaAβ(1-42)LI/ARDSInhibitorinhibitorinhibit

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