2. Inhibitory Antibodies
  3. Tamtuvetmab

Tamtuvetmab  (Synonyms: 坦妥维单抗; AT-005; AT005)

目录号: HY-P99579 纯度: 97%
COA

摩尔计算器

Tamtuvetmab (AT-005) 是一种抗 CD52 的犬用金色单抗。Tamtuvetmab 可增加无进展生存期 (PFS)，对患有稚嫩 T 细胞淋巴瘤 (LSA) 犬表现出疗效。Tamtuvetmab 已被兽医批准。

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CAS No. : 1608122-71-9

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规格 价格 是否有货 数量
1 mg ￥4000
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5 mg   询价  
10 mg   询价  

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Tamtuvetmab 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Tamtuvetmab (AT-005) is a caninised blontuvetmab against CD52. Tamtuvetmab increases progression-free survival (PFS), exhibits in vivo efficacy in dogs with naïve T-cell lymphoma (LSA). Tamtuvetmab has been approved by veterinary[1][2].

同型

Canis IgG2 kappa
种属

Caninized

IC50 & Target

CD52[1]
体内研究
(In Vivo)

Tamtuvetmab (5 mg/mL, 7.5-30 mL; 静脉注射; 注射 15-30 分钟) 对患有幼稚 T 细胞淋巴瘤 (LSA) 的狗有体内疗效，但会导致呕吐、体重减轻、腹泻、嗜睡、食欲下降和厌食[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: T-cell LSA Model in Dog[1]
Dosage: 5 mg/mL, 7.5-30 mL; Dogs weighing for 2-15 kg received 7.5 mL, for 15.1-30 kg received 15 mL, for 30.1-45 kg received 22.5 mL, for 45.1-60 kg received 30 mL
Administration: Intravenous injection; 15-30 min
Result: Showed in vivo efficacy with severe side effect.
CAS 号
性状

液体

颜色

Colorless to light yellow

中文名称

坦妥维单抗
运输条件

Shipping with dry ice.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
Format
  • IgG2-Vkappa-Clambda
纯度 & 产品资料
参考文献

Tamtuvetmab 相关分类

  • 摩尔计算器

  • 稀释计算器

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Tamtuvetmab1608122-71-9AT-005 AT005坦妥维单抗AT005AT 005OthersInhibitorinhibitorinhibit

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