2. GPCR/G Protein Neuronal Signaling
  3. Dopamine Receptor
  4. TAT-D1 peptide

TAT-D1 peptide 是一种选择性的 D1-D2 异质拮抗剂。TAT-D1 peptide 通过其独特的氨基酸序列，特别是 D1 受体 C 末端的两个谷氨酸残基，与 D2 受体的特定结构域相互作用，从而破坏 D1-D2 受体异源二聚体。TAT-D1 peptide 可用于 D1-D2 受体异源二聚体在调节抑郁和焦虑样行为中的研究。

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Custom Peptide Synthesis

TAT-D1 peptide Chemical Structure

TAT-D1 peptide Chemical Structure

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TAT-D1 peptide 相关抗体

Top Publications Citing Use of Products

查看 Dopamine Receptor 亚型特异性产品:

查看所有亚型
Dopamine Receptor D1 Receptor D2 Receptor D3 Receptor D4 Receptor D5 Receptor

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

TAT-D1 peptide is a selective D1-D2 heterogeneous antagonist. TAT-D1 peptide destroys the heterodimer of the D1-D2 receptor by interacting with the specific domain of the D2 receptor through its unique amino acid sequence, in particular the two glutamate residues at the C terminal of the D1 receptor. TAT-D1 peptide can be used to study the role of D1-D2 receptor heterodimers in the regulation of depressive and anxiety-like behaviors[1].

分子量

3474.94

Formula

C144H257N57O43
Sequence

Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-Pro-Gln-Gly-Ser-Ser-Glu-Asp-Leu-Lys-Lys-Glu-Glu-Ala-Ala-Gly-Ile-Ala-Arg-Pro-Leu
Sequence Shortening

GRKKRRQRRRPQGSSEDLKKEEAAGIARPL
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

TAT-D1 peptide 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

TAT-D1 peptideDopamine ReceptorDopamineantagonistsheterodimersdepressionanxietyInhibitorinhibitorinhibit

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产品名称：
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目录号：
HY-P10405
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