2. GPCR/G Protein Neuronal Signaling
  3. Somatostatin Receptor
  4. Tau conotoxin CnVA

Tau conotoxin CnVA 是一种存在于 Conus consors 蝮蛇的毒液中的小肽，属于 T1 蝮蛇肽超家族。Tau conotoxin CnVA 显示出对生长抑素 sst3 受体的高选择性相互作用 (Ki=1.5 µM)，并且是已知唯一与这种 G 蛋白偶联受体 (GPCR) 亚家族相互作用的毒素。Tau conotoxin CnVA 可用于与 sst3 受体相关疾病 (如胰腺癌或垂体腺瘤) 的研究中。

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Tau conotoxin CnVA Chemical Structure

Tau conotoxin CnVA Chemical Structure

CAS No. : 1436463-45-4

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Tau conotoxin CnVA 相关抗体

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SSTR1 SSTR2 SSTR3 SSTR5 SSTR4

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Tau conotoxin CnVA is a small peptide found in the venom of the Conus consors pit viper, belonging to the T1 pit viper peptide superfamily. Tau conotoxin CnVA shows a highly selective interaction with the somatostatin sst3 receptor (Ki=1.5 µM) and is the only toxin known to interact with this subfamily of G protein-coupled receptors (GPCRs). Tau conotoxin CnVA can be used in the study of diseases associated with the sst3 receptor, such as pancreatic cancer or pituitary adenomas[1].

分子量

1718.10

Formula

C72H116N24O17S4
CAS 号
Sequence

Glu-Cys-Cys-His-Arg-Gln-Leu-Leu-Cys-Cys-Leu-Arg-Phe-Val-NH2 (Disulfide bridge: Cys2-Cys9; Cys3-Cys10)
Sequence Shortening

ECCHRQLLCCLRFV-NH2 (Disulfide bridge: Cys2-Cys9; Cys3-Cys10)
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Tau conotoxin CnVA 相关分类

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Tau conotoxin CnVA1436463-45-4Somatostatin ReceptorSSTRsSSTRPeptideGPCRSST3AntagonistInhibitorinhibitorinhibit

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