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  3. 多肽及其衍生物
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  5. 多肽连接子
  6. Tetraglycine hydrochloride

Tetraglycine hydrochloride 是由四个甘氨酸单体组成的寡肽。

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Custom Peptide Synthesis

Tetraglycine hydrochloride Chemical Structure

Tetraglycine hydrochloride Chemical Structure

CAS No. : 38126-71-5

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规格 是否有货
50 mg   询价  
100 mg   询价  
250 mg   询价  

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Tetraglycine hydrochloride 的其他形式现货产品:

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Other Forms of Tetraglycine hydrochloride:

Tetraglycine hydrochloride 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Tetraglycine hydrochloride is a oligopeptide composed of four glycine monomers[1].

体内研究
(In Vivo)

Tetraglycine 和 Triglycine (1.0 μmol甘氨酸/g体重 (246.22 mg/kg)，注射到中央静脉)比注射 Glycine (HY-Y0966) 或 Diglycine 导致的肾脏中的甘氨酸浓度更高[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Male Sprague-Dawley rats (270-300 g)[1]
Dosage: 1.0 μmol glycine/g body wt (246.22 mg/kg)
Administration: IV, injected over a period of 30 s
Result: Five minutes after the Tetraglycine injection, there were accumulations of diglvcine, triglvcine, and Tetraglycine in the kidney.
分子量

282.68

Formula

C8H15ClN4O5
CAS 号
性状

固体

颜色

White to off-white

Sequence Shortening

GGGG
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Sealed storage, away from moisture and light, under nitrogen

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen)

Solvent & Solubility
细胞实验： 

H2O

Peptide Solubility and Storage Guidelines:

1.  Calculate the length of the peptide.

2.  Calculate the overall charge of the entire peptide according to the following table:

  Contents Assign value
Acidic amino acid Asp (D), Glu (E), and the C-terminal -COOH. -1
Basic amino acid Arg (R), Lys (K), His (H), and the N-terminal -NH2 +1
Neutral amino acid Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q) 0

3.  Recommended solution:

Overall charge of peptide Details
Negative (<0) 1.  Try to dissolve the peptide in water first.
2.  If water fails, add NH4OH (<50 μL).
3.  If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (>0) 1.  Try to dissolve the peptide in water first.
2.  If water fails, try dissolving the peptide in a 10%-30% acetic acid solution.
3.  If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0) 1.  Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first.
2.  For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.
纯度 & 产品资料
参考文献

Tetraglycine hydrochloride 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Tetraglycine38126-71-5OthersInhibitorinhibitorinhibit

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目录号：
HY-W142467A
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