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  3. Thrombin inhibitor 7

Thrombin inhibitor 7 是一种有效的 FXIIa 抑制剂,对 FXIIa 和 FXIa 的 IC50 值分别为 28 nM 和 >132 µM。Thrombin inhibitor 7 具有低细胞毒性。

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Thrombin inhibitor 7 Chemical Structure

Thrombin inhibitor 7 Chemical Structure

CAS No. : 2866508-00-9

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  • 生物活性

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生物活性

Thrombin inhibitor 7 is a potent FXIIa inhibitor with IC50 values of 28 nM, >132 µM for FXIIa and FXIa, respectively. Thrombin inhibitor 7 shows low cytotoxicity[1].

体外研究
(In Vitro)

Thrombin inhibitor 7 (compound 33b) (0-300 µM; 24 h) shows low cytotoxicity in HepG2, A549 cells[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Cytotoxicity Assay[1]

Cell Line: HepG2, A549 cells
Concentration: 0-300 µM
Incubation Time: 24 h
Result: Showed low cytotoxicity in HepG2, A549 cells.
分子量

465.51

Formula

C26H23N7O2

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

Thrombin inhibitor 7 相关分类

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Thrombin inhibitor 7
目录号:
HY-152150
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