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Timcodar是一种大环内酯类试剂,研究表明,在脂肪生成过程中,timcodar能显著抑制脂肪积累,其效果与雷帕霉素相似。但与雷帕霉素不同的是,timcodar不会引起免疫抑制和葡萄糖抵抗。此外,timcodar能有效抑制脂肪生成转录调节因子PPAR??和C/EBP??,从而抑制涉及脂肪积累的基因。这些研究为timcodar作为潜在的抗肥胖疗法奠定了基础,因为肥胖正成为一个全球性流行病。

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Timcodar Chemical Structure

Timcodar Chemical Structure

CAS No. : 179033-51-3

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Other Forms of Timcodar:

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Timcodar is a macrolide agent, and studies have shown that during adipogenesis, timcodar can significantly inhibit fat accumulation, with an effect similar to that of rapamycin. However, unlike rapamycin, timcodar does not cause immunosuppression and glucose resistance. In addition, timcodar can effectively inhibit the adipogenic transcriptional regulators PPAR?? and C/EBP??, thereby inhibiting genes involved in fat accumulation. These studies lay the foundation for timcodar as a potential anti-obesity therapy, as obesity is becoming a global epidemic.

分子量

749.29

Formula

C43H45ClN4O6

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

Timcodar 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Timcodar
目录号:
HY-13766
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