2. Metabolic Enzyme/Protease
  3. Endogenous Metabolite
  4. TMC-205

TMC-205 是一种天然真菌代谢产物，具有抗肿瘤细胞增殖活性。TMC-205 是 SV40 启动子的转录上调因子。

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TMC-205 Chemical Structure

TMC-205 Chemical Structure

CAS No. : 403646-00-4

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TMC-205 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

TMC-205 is a natural fungal metabolite with antiproliferative activity against cancer cell lines. TMC-205 is a transcriptional up-regulator of SV40 promoter[1].

IC50 & Target[1]

Microbial Metabolite

 

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
HCT-116 GI50
68 μM
Compound: 1, TMC-205
Antiproliferative activity against human HCT116 cells assessed as growth inhibition after 72 hrs by MTS assay
Antiproliferative activity against human HCT116 cells assessed as growth inhibition after 72 hrs by MTS assay
[PMID: 25147604]
分子量

227.26

Formula

C14H13NO2
CAS 号
结构分类
初始来源

an unidentified fungus.
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

TMC-205 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

TMC-205403646-00-4TMC205TMC 205Endogenous Metabolitefungal metaboliteantiproliferativecancer cell linesSV40 promoterInhibitorinhibitorinhibit

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产品名称：
TMC-205
目录号：
HY-114646
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