1. Cell Cycle/DNA Damage Apoptosis
  2. Topoisomerase Apoptosis
  3. Topoisomerase II inhibitor 20 TFA

Topoisomerase II inhibitor 20 TFA 是一种有效的拓扑异构酶 II (Topoisomerase II) 抑制剂,IC50 为 0.98 µM。Topoisomerase II inhibitor 20 TFA 可诱导细胞凋亡 (apoptosis) 且具有广谱抗癌活性。

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Topoisomerase II inhibitor 20 TFA Chemical Structure

Topoisomerase II inhibitor 20 TFA Chemical Structure

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生物活性

Topoisomerase II inhibitor 20 TFA is a potent topoisomerase II inhibitor with IC50 of 0.98 µM. Topoisomerase II inhibitor 20 TFA can induce apoptosis and has broad-spectrum anticancer activity[1].

IC50 & Target[1]

Topoisomerase II

0.98 μM (IC50)

分子量

573.54

Formula

C24H24F5N5O4S

性状

固体

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Topoisomerase II inhibitor 20 TFA
目录号:
HY-158061A
需求量: