2. Metabolic Enzyme/Protease
  3. Tryptophan Hydroxylase
  4. TPH1-IN-1

TPH1-IN-1 (compound 40) 是黄嘌呤衍生物，是色氨酸羟化酶 (Tryptophan Hydroxylase) TPH1 抑制剂 (IC50: 110.1 nM)。TPH1-IN-1 具有良好的体外活性和肝微粒体稳定性，有效抑制 T3-L1 细胞的脂肪细胞分化。

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TPH1-IN-1 Chemical Structure

TPH1-IN-1 Chemical Structure

CAS No. : 3040015-86-6

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TPH1-IN-1 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

TPH1-IN-1 (compound 40) is a xanthine derivative and an inhibitor of tryptophan hydroxylase TPH1 (IC50: 110.1 nM). TPH1-IN-1 has good in vitro activity and liver microsome stability, and effectively inhibits adipocyte differentiation of T3-L1 cells[1].

IC50 & Target

IC50: 110.1 nM (TPH1)[1]
分子量

450.47

Formula

C21H18N6O4S
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

TPH1-IN-1 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

TPH1-IN-13040015-86-6Tryptophan HydroxylaseFatty liverObesityTPH inhibitorXanthineInhibitorinhibitorinhibit

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