2. PI3K/Akt/mTOR Stem Cell/Wnt
  3. GSK-3
  4. Triptonodiol

Triptonodiol 可从 Trypterygium wilfordii 中分离得到。Triptonodiol 具有抗炎和抗癌活性。Triptonodiol 抑制 GSK 的生物学活性。

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Triptonodiol Chemical Structure

Triptonodiol Chemical Structure

CAS No. : 117456-87-8

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1 mg ￥5170
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Triptonodiol 相关抗体

Top Publications Citing Use of Products

查看 GSK-3 亚型特异性产品:

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GSK-3 GSK-3α GSK-3β

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Triptonodiol can be isolated from Trypterygium wilfordii. Triptonodiol has anti-inflammatory and anti-cancer activity. Triptonodiol inhibits the biological activity of GSK[1][2].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
A549 IC50
21.59 μM
Compound: 3
Cytotoxicity against human A549 cells after 48 hrs by MTT assay
Cytotoxicity against human A549 cells after 48 hrs by MTT assay
[PMID: 27133593]
Bcap37 IC50
> 100 μM
Compound: 3
Cytotoxicity against human Bcap37 cells after 48 hrs by MTT assay
Cytotoxicity against human Bcap37 cells after 48 hrs by MTT assay
[PMID: 27133593]
Hep 3B2 IC50
28.69 μM
Compound: 3
Cytotoxicity against human Hep3B cells after 48 hrs by MTT assay
Cytotoxicity against human Hep3B cells after 48 hrs by MTT assay
[PMID: 27133593]
HepG2 IC50
21.89 μM
Compound: 3
Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay
Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay
[PMID: 27133593]
MCF7 IC50
23.23 μM
Compound: 3
Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay
Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay
[PMID: 27133593]
U-251 IC50
> 100 μM
Compound: 3
Cytotoxicity against human U251 cells after 48 hrs by MTT assay
Cytotoxicity against human U251 cells after 48 hrs by MTT assay
[PMID: 27133593]
分子量

346.46

Formula

C21H30O4
CAS 号
性状

固体

颜色

White to off-white

结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

-20°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

纯度 & 产品资料
参考文献

Triptonodiol 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Triptonodiol117456-87-8GSK-3Glycogen synthase kinase-3Glycogen synthase kinase 3Trypterygium wilfordiicancerinflammationGSKNSCLCInhibitorinhibitorinhibit

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