2. Anti-infection
  3. Parasite
  4. Trypanothione synthetase-IN-4

Trypanothione synthetase-IN-4 

目录号: HY-151149
产品使用指南

摩尔计算器

Trypanothione synthetase-IN-4 是一个 L. infantum TryS 抑制剂，其活性依赖于多胺底物的浓度。Trypanothione synthetase-IN-4 具有较强的抗 leishmanicidal 活性，其 EC50 值为 0.6 μM，选择性指数为 35。Trypanothione synthetase-IN-4 可用于利什曼病的研究。

MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

Trypanothione synthetase-IN-4 Chemical Structure

Trypanothione synthetase-IN-4 Chemical Structure

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 是否有货
50 mg   询价  
100 mg   询价  
250 mg   询价  

* Please select Quantity before adding items.

Customer Review

Trypanothione synthetase-IN-4 相关抗体

Top Publications Citing Use of Products

查看 Parasite 亚型特异性产品:

查看所有亚型
Amebae Coccidia Leishmania Mite Plasmodium Toxoplasma Trypanosoma Schistosome

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Trypanothione synthetase-IN-4 is a L. infantum trypanothione synthetase (TryS) inhibitor, and the activity is dependent on the concentration of the polyamine substrate. Trypanothione synthetase-IN-4 has potent antileishmanicidal activity with an EC50 value of 0.6 μM and a selectivity index of 35. Trypanothione synthetase-IN-4 can be used for the research of leishmaniasis[1].

IC50 & Target

Leishmania

 

体外研究
(In Vitro)

Trypanothione synthetase-IN-4 (15 μM) has activity against LiTryS for three substrates (ATP, GSH and Spd) with IC50 values of 7.3 μM, 7.8 μM and 5.5 μM, respectively[1].
Trypanothione synthetase-IN-4 (25 μM, 24 h) has antileishmanial activity with an EC50 value of 0.4 μM in axenic amastigotes of L. infantum[1].
Trypanothione synthetase-IN-4 (25 μM, 72 h) is active against intracellular amastigotes (EC50=0.6 μM) and has a high selectivity index of 35.5[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Trypanothione synthetase-IN-4 相关抗体:

Cell Cytotoxicity Assay[1]

Cell Line: HepG2 (human hepatoma cell line)
Concentration: 25 μM
Incubation Time: 72 h
Result: Showed antileishmanial activity with an EC50 value of 0.4 μM in axenic amastigotes of L. infantum.
分子量

573.63

Formula

C29H52INO2
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Trypanothione synthetase-IN-4 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Trypanothione synthetase-IN-4ParasiteL. infantumtrypanothione synthetase (TryS)polyamineanti-leishmanicidalparasitesInhibitorinhibitorinhibit

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称：

  

* 需求量：

* 客户姓名：

 

* Email：

* 电话：

 

* 公司或机构名称：

   留言给我们：

Bulk Inquiry

Inquiry Information

产品名称：
Trypanothione synthetase-IN-4
目录号：
HY-151149
需求量：

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

   产品名称：

  

* Lot #：

* 客户姓名：

 

* Email：

   电话：

 

* 部门：

* 公司或机构名称：

 

   留言给我们：

Request for HNMR Report

We have received your request and will respond to you as soon as possible.

嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z