2. Apoptosis
  3. Thymidylate Synthase Apoptosis
  4. TS-IN-6

TS-IN-6 (Compound 10) 是一种胸苷酸合成酶 (TS) 抑制剂，其 IC50 值为 0.54  μM，具有显著的抗增殖活性。TS-IN-6 能诱导细胞周期 G1 期阻滞和凋亡 (apoptosis) (早期及晚期凋亡率显著增加)，可以用于结肠癌、乳腺癌和肝癌等癌症的研究。

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TS-IN-6 Chemical Structure

TS-IN-6 Chemical Structure

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

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Customer Review

TS-IN-6 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

TS-IN-6 (Compound 10) is a thymidylate synthase (TS) inhibitor with an IC50 value of 0.54  μM, demonstrating significant antiproliferative activity. TS-IN-6 induces G1 phase cell cycle arrest and apoptosis (marked by substantial increases in both early and late apoptotic rates) and shows potential for research on cancers such as colon, breast, and liver cancers[1].

IC50 & Target

IC50: 0.54 μM (TS)[1].
分子量

540.59

Formula

C29H22F2N6OS
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

TS-IN-6 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

TS-IN-6Thymidylate SynthaseApoptosisapoptosisHepG2MCF-7HEK-293HCT-116Colon cancerliver cancerbreast cancerInhibitorinhibitorinhibit

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目录号：
HY-172172
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