1. Anti-infection
  2. Bacterial
  3. Tunicamycin V

Tunicamycin V  (Synonyms: Tunicamycin A)

目录号: HY-N8395 纯度: ≥95.0%
COA 产品使用指南

Tunicamycin V (Tunicamycin A) 是一种核苷天然产物,可抑制细菌 phospho-N-acetylmuramyl-pentapeptide transferase (MraY)IC50 为 0.35 μM。Tunicamycin V 具有抗菌活性。

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Tunicamycin V Chemical Structure

Tunicamycin V Chemical Structure

CAS No. : 66054-36-2

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1 mg ¥9300
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MCE 顾客使用本产品发表的 2 篇科研文献

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Tunicamycin V (Tunicamycin A) is a nucleoside natural product that inhibits bacterial phospho-N-acetylmuramyl-pentapeptide transferase (MraY) with an IC50 of 0.35?μM. Tunicamycin V has antibacterial activties[1][2].

IC50 & Target

IC50: 0.35 μM (phospho-N-acetylmuramyl-pentapeptide transferase (MraY))[1]

体外研究
(In Vitro)

Tunicamycins are nucleoside natural products isolated from the fermentation broths of Streptomyces lysosuperficus in 1971 and exhibit a variety of biological properties including antibacterial, antiviral, antifungal, and antitumor activities. Tunicamycins strongly inhibit UDP-N-acetylglucosamine (GlcNAc): polyprenol phosphate translocase, the enzyme responsible for the first N-acetylglucosamination of the N-linked glycopeptide in endothelial reticulum (ER)[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

844.94

Formula

C39H64N4O16

CAS 号
性状

固体

颜色

White to off-white

中文名称

衣霉素V;衣霉素A

结构分类
初始来源

Streptomyces xinghaiensis SCSIO S15077

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
纯度 & 产品资料

纯度: ≥95.0%

参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Tunicamycin V
目录号:
HY-N8395
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