1. Apoptosis
  2. TNF Receptor
  3. Utomilumab

Utomilumab  (Synonyms: 乌托鲁单抗; PF 05082566)

目录号: HY-P99056 纯度: 99.33%
COA

Utomilumab (PF 05082566) 是一种人源的 IgG2 mAb 激动剂,靶向T 细胞共刺激受体 4-1BB/CD137。Utomilumab 可用于复发/难治性滤泡性淋巴瘤 (FL) 和其他 CD20+ 非霍奇金淋巴瘤 (NHL) 的研究。

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CAS No. : 1417318-27-4

1.  客户无需承担相应的运输费用。

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     可免费申领三个不同产品的试用装。

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规格 价格 是否有货 数量
1 mg ¥3000
In-stock
5 mg ¥7800
In-stock
10 mg   询价  
50 mg   询价  

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Customer Review

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Utomilumab (PF 05082566) is a fully human IgG2 mAb agonist of the T-cell costimulatory receptor 4-1BB/CD137. Utomilumab can be used for the research of relapsed/refractory follicular lymphoma (FL) and other CD20+ non-Hodgkin lymphomas (NHL)[1][2].

同型

Human IgG2 Lambda2

IC50 & Target

4-1BB

 

Clinical Trial
CAS 号
性状

液体

颜色

Colorless to light yellow

中文名称

乌托鲁单抗

运输条件

Shipping with dry ice.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

Format
  • Human IgG2 lambda
Biological Activity
  • Immobilized 4-1BB/TNFRSF9 Protein, Human can bind Utomilumab. The EC50 for this effect is 6.92 ng/mL.
纯度 & 产品资料

纯度: 99.33%

参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Utomilumab
目录号:
HY-P99056
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