2. Membrane Transporter/Ion Channel
  3. Monoamine Transporter
  4. Valbenazine tosylate

Valbenazine tosylate  (Synonyms: NBI-98854 tosylate)

目录号: HY-16771A
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摩尔计算器

Valbenazine tosylate (NBI-98854 tosylate) 是一种囊泡单胺类转运 2 (VMAT2) 抑制剂，Ki 为 110-190 nM。

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Valbenazine tosylate Chemical Structure

Valbenazine tosylate Chemical Structure

CAS No. : 1639208-54-0

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Valbenazine tosylate 的其他形式现货产品:

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Other Forms of Valbenazine tosylate:

Valbenazine tosylate 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Valbenazine tosylate (NBI-98854 tosylate) is a vesicular monoamine transporter 2 (VMAT2) inhibitor with the Ki of 110-190 nM[1].

体外研究
(In Vitro)

Valbenazine exhibits VMAT2 binding affinity in rat striatum and human platelets with Kis of 110 and 150 nM, respectively[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Valbenazine tosylate 相关抗体:
体内研究
(In Vivo)

Valbenazine (10 mg/kg; orally) induces ptosis (primarily an adrenergic response) and increases plasma prolactin primarily a dopaminergic response in rats[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Clinical Trial
分子量

762.97

Formula

C38H54N2O10S2
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Valbenazine tosylate 相关分类

  • 摩尔计算器

  • 稀释计算器

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Valbenazine1639208-54-0NBI-98854NBI98854NBI 98854Monoamine TransporterHuntingtondiseasevesicularmonoaminetransporterVMAT2Inhibitorinhibitorinhibit

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