1. Stem Cell/Wnt Epigenetics Cell Cycle/DNA Damage Autophagy Anti-infection Neuronal Signaling Apoptosis Metabolic Enzyme/Protease
  2. Organoid HDAC Autophagy Mitophagy HIV Notch Apoptosis Endogenous Metabolite
  3. Valproic acid sodium (Standard)

Valproic acid sodium (Standard)  (Synonyms: 丙戊酸钠(Standard))

目录号: HY-10585AR 纯度: ≥98%
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Valproic acid (sodium) (Standard)是 Valproic acid (sodium) 的分析标准品。本产品用于研究及分析应用。Valproic acid (Sodium Valproate) sodium 是一种具有口服活性的 HDAC 抑制剂,IC50 值为 0.5-2 mM,抑制 HDAC1 的活性,(IC50,400 μM),同时可诱导 HDAC2 的降解。Valproic acid sodium 激活 Notch1 信号并抑制小细胞肺癌 (SCLC) 细胞的增殖。Valproic acid sodium 可用于癫痫、双相情感障碍、代谢疾病、HIV 感染和偏头痛等的研究。

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Valproic acid sodium (Standard) Chemical Structure

Valproic acid sodium (Standard) Chemical Structure

CAS No. : 1069-66-5

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规格 价格 是否有货
25 mg ¥352
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50 mg ¥528
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100 mg ¥800
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250 mg ¥1600
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Other Forms of Valproic acid sodium (Standard):

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生物活性

Valproic acid (sodium) (Standard) is the analytical standard of Valproic acid (sodium). This product is intended for research and analytical applications. Valproic acid (Sodium Valproate) sodium is an orally active HDAC inhibitor, with IC50 in the range of 0.5 and 2 mM, also inhibits HDAC1 (IC50, 400 μM), and induces proteasomal degradation of HDAC2. Valproic acid sodium activates Notch1 signaling and inhibits proliferation in small cell lung cancer (SCLC) cells. Valproic acid sodium is used in the treatment of epilepsy, bipolar disorder, metabolic disease, HIV infection and prevention of migraine headaches.

分子量

166.19

Formula

C8H15NaO2

CAS 号
中文名称

丙戊酸钠(Standard);丙戊酸钠盐(Standard);定百痉(Standard);癫扑净(Standard);抗癫灵(Standard);敌白痉(Standard);2-丙基戊酸钠(Standard)

结构分类
初始来源
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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