2. Protein Tyrosine Kinase/RTK
  3. VEGFR Tie
  4. Vanucizumab

Vanucizumab  (Synonyms: 伐努赛珠单抗; Anti-Human VEGFA Recombinant Antibody; RO5520985)

目录号: HY-P99330 纯度: 95.00%
COA

摩尔计算器

Vanucizumab 是一种首创的双特异性 IgG1 单克隆抗体，可同时阻断 VEGF-A 和血管生成素-2 (Ang-2) 与其受体相互作用。 Vanucizumab 具有抗血管生成和抗癌作用。

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CAS No. : 1448221-05-3

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 价格 是否有货 数量
1 mg ￥3500
In-stock
5 mg ￥9100
In-stock
10 mg   询价  
50 mg   询价  

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Customer Review

Vanucizumab 相关抗体

Top Publications Citing Use of Products

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VEGFR1/Flt-1 VEGFR2/KDR/Flk-1 VEGFR3/Flt-4

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Tie2

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Vanucizumab is a first-in-class, bispecific IgG1-like monoclonal antibody that simultaneously blocks VEGF-A and angiopoietin-2 (Ang-2) from interacting with their receptors. Vanucizumab has antiangiogenic and anticancer effects[1].

同型

Human IgG1 kappa
推荐同型对照抗体
种属

Humanized
体内研究
(In Vivo)

Vanucizumab (20mg /kg;i.p。每周1次;6周) 显示肿瘤生长抑制和诱导肿瘤停滞[2]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: SCID beige mice bearing Colo205 cells[2]
Dosage: 20 mg/kg
Administration: i.p.; once weekly; for 6 weeks
Result: Showed tumor growth inhibition.
Clinical Trial
CAS 号
性状

液体

颜色

Colorless to light yellow

中文名称

伐努赛珠单抗
运输条件

Shipping with dry ice.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
Format
  • IgG1-kappa-lambda with half-IG VL-CH1/VH-CK crossover
纯度 & 产品资料
参考文献

Vanucizumab 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Vanucizumab1448221-05-3Anti-Human VEGFA Recombinant Antibody RO5520985伐努赛珠单抗RO5520985RO 5520985RO-5520985VEGFRTieVascular endothelial growth factor receptorAngiopoietin receptorangiopoietin-2VEGF-Amonoclonal antibodyantiangiogenic and anticancer effectsInhibitorinhibitorinhibit

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