1. Protein Tyrosine Kinase/RTK PI3K/Akt/mTOR
  2. VEGFR Akt
  3. VEGFR-2/AKT-IN-1

VEGFR-2/AKT-IN-1 (compound 17) 是 VEGFR-2AKT 的双重抑制剂,其 IC50 分别为 0.164 μM 和 0.452 μM。VEGFR-2/AKT-IN-1 具有抗肿瘤活性。

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VEGFR-2/AKT-IN-1 Chemical Structure

VEGFR-2/AKT-IN-1 Chemical Structure

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     可免费申领三个不同产品的试用装。

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查看 VEGFR 亚型特异性产品:

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

VEGFR-2/AKT-IN-1 (compound 17) is a dual inhibitor of VEGFR-2 and AKT, with the IC50s of 0.164 μM and 0.452 μM, respectively. VEGFR-2/AKT-IN-1 has antitumor activity[1].

IC50 & Target

VEGFR2

0.164 μM (IC50)

分子量

409.45

Formula

C16H11N9OS2

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
VEGFR-2/AKT-IN-1
目录号:
HY-161861
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