2. Protein Tyrosine Kinase/RTK
  3. VEGFR PDGFR
  4. VEGFR-2-IN-44

VEGFR-2-IN-44 (compound 4b) 是一种选择性 VEGF-R2 (Flk-1) 抑制剂，IC50 值为 70 nM。VEGFR-2-IN-44 还抑制 PDGF-Rβ，IC50 为 920 nM。

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VEGFR-2-IN-44 Chemical Structure

VEGFR-2-IN-44 Chemical Structure

CAS No. : 288144-20-7

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VEGFR-2-IN-44 相关抗体

Top Publications Citing Use of Products

查看 VEGFR 亚型特异性产品:

查看所有亚型
VEGFR1/Flt-1 VEGFR2/KDR/Flk-1 VEGFR3/Flt-4

查看 PDGFR 亚型特异性产品:

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PDGFR PDGFRβ PDGFRα

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

VEGFR-2-IN-44 (compound 4b) is a selective VEGF-R2 (Flk-1) inhibitor with an IC50 value of 70 nM. VEGFR-2-IN-44 also inhibits PDGF-Rβ with an IC50 of 920 nM[1].

IC50 & Target[1]

Flk-1

70 nM (IC50)

PDGFR-β

920 nM (IC50)

分子量

343.22

Formula

C17H15BrN2O
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

VEGFR-2-IN-44 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

VEGFR-2-IN-44288144-20-7VEGFRPDGFRVascular endothelial growth factor receptorPlatelet-derived growth factor receptorVEGFR2 (Flk-1)PDGF-RβInhibitorinhibitorinhibit

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目录号：
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