2. PROTAC
  3. E3 Ligase Ligand-Linker Conjugates
  4. VH032-O-C2-NH-Boc

VH032-O-C2-NH-Boc 是 Boc 修饰的 VH032 (HY-120217)，可作为 VHL 的配体，募集 von Hippel-Lindau (VHL) 蛋白。VH032-O-C2-NH-Boc 在酸性条件下会脱除保护基团，直接用于 PROTAC 分子合成。VH032-O-C2-NH-Boc 是合成基于 VHL 配体的 PROTAC关键中间体。

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VH032-O-C2-NH-Boc Chemical Structure

VH032-O-C2-NH-Boc Chemical Structure

CAS No. : 2409007-41-4

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VH032-O-C2-NH-Boc 相关抗体

Top Publications Citing Use of Products

查看 E3 Ligase Ligand-Linker Conjugates 亚型特异性产品:

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von Hippel-Lindau (VHL) MDM2 Cereblon cIAP1 Aryl Hydrocarbon Receptor TRIM21

  • 生物活性

  • 纯度 & 产品资料

生物活性

VH032-O-C2-NH-Boc is a Boc-modified VH032 (HY-120217) that serves as a ligand for VHL and recruits von Hippel-Lindau (VHL) proteins. VH032-O-C2-NH-Boc will remove the protecting group under acidic conditions and can be directly used in PROTAC molecule synthesis. VH032-O-C2-NH-Boc is a key intermediate in the synthesis of PROTAC based on VHL ligand.

分子量

631.78

Formula

C31H45N5O7S
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料

VH032-O-C2-NH-Boc 相关分类

  • 摩尔计算器

  • 稀释计算器

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浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

VH032-O-C2-NH-Boc2409007-41-4E3 Ligase Ligand-Linker ConjugatesLigands for E3 LigaseInhibitorinhibitorinhibit

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