2. Metabolic Enzyme/Protease
  3. LDLR
  4. VH4127

VH4127 是一种针对低密度脂蛋白受体 (LDLR) 的环状肽，对 hLDLR 的 KD 为 18 nM。VH4127 带有非天然氨基酸残基，可特异性结合啮齿动物和人类表皮生长因子 (EGF) LDLR 同源域。

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Custom Peptide Synthesis

VH4127 Chemical Structure

VH4127 Chemical Structure

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

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Customer Review

VH4127 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

VH4127 is a cyclic peptide targeting the low density lipoprotein receptor (LDLR) with a KD of 18 nM for hLDLR. VH4127, bearing non-natural amino acid residues, specifically binds to rodent and human epidermal growth factor (EGF) homology domain of LDLR[1][2].

IC50 & Target[1]

hLDLR

18 nM (Kd)

分子量

1048.37

Formula

C41H73N15O9S4
Sequence

cyclo[{d-Cys}-Met-{Thz}-Arg-Leu-Arg-Gly-{Pen}]
Sequence Shortening

cyclo[{d-Cys}-M-{Thz}-RLRG-{Pen}]
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

VH4127 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

VH4127VH 4127VH-4127LDLRLow-density lipoprotein receptorcyclic peptidelow density lipoproteinnon-natural amino acidInhibitorinhibitorinhibit

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产品名称：
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目录号：
HY-P10697
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