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Asinex Covalent Inhibitors Library

Cat. No.: HY-L0118V

A unique set of molecules containing mild electrophilic moieties that covalently interact with amino acid residues in the target protein. The diversity of our compounds for covalent drug discovery ranges from natural product-like scaffolds to macrocycles, creating multiple opportunities in hit generation for a selected target.

  • Chinese National Compound Library
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Biological activity

•   A unique set of 942 covalent inhibitors library.

•   All compounds possess a reactive “warhead” which is designed to interact with a nucleophilic residue at the binding site. Examples of efficient electrophilic warheads include chloroacetamides, acrylamides, epoxides, nitriles, and electron-deficient ketones.

•   Due to the intrinsic reactivity of molecules containing a covalent reactive group, rigorous quality control and efficient compound management logistics (storage and handling) are implemented to ensure consistent screening results.

•   All compounds can be readily followed with analogues either from stock or from new syntheses.

•   Databases and compounds are provided by Asinex.

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  • Chinese National Compound Library
  • Chinese National Compound Library

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产品名称：
Asinex Covalent Inhibitors Library
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HY-L0118V
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