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  4. VUF5834

VUF5834 是一种非肽类趋化因子受体CXCR3拮抗剂，具有非竞争性拮抗和反向激动活性。VUF5834可阻断CXCL10和CXCL11在人CXCR3上的作用，对CXCR3表现出非竞争性拮抗和反向激动特性，除TAK-779外，对啮齿动物CXCR3的亲和力略低于灵长类动物CXCR3。

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VUF5834 Chemical Structure

VUF5834 Chemical Structure

CAS No. : 860002-95-5

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VUF5834 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

VUF5834 is a non-peptide chemokine receptor CXCR3 antagonist with non-competitive antagonistic and inverse agonistic activities. VUF5834 blocks the effects of CXCL10 and CXCL11 on human CXCR3, exhibits non-competitive antagonistic and inverse agonistic properties to CXCR3, and, except for TAK-779, has a slightly lower affinity for rodent CXCR3 than for primate CXCR3.

分子量

515.69

Formula

C31H41N5O2
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

VUF5834 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

VUF5834860002-95-5VUF 5834VUF-5834OthersInhibitorinhibitorinhibit

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产品名称：
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目录号：
HY-113730
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