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  3. WAY 163909 hydrochloride

WAY 163909 hydrochloride 是一种有效的 5-羟色胺受体 2C (5-HT2C) 激动剂,EC50 为 8 nM,最大功效为 90%,而对 5-HT2A 受体的活性最小。其选择性进一步体现在 5-HT2C 的 Ki 值为 10.5 nM,而 5-HT2A (212 nM)、5-HT7 (343 nM) 和 5-HT2B (485 nM) 的 Ki 值较高,并且对其他各种受体缺乏显著活性。

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WAY 163909 hydrochloride Chemical Structure

WAY 163909 hydrochloride Chemical Structure

CAS No. : 428868-35-3

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Other Forms of WAY 163909 hydrochloride:

  • 生物活性

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生物活性

WAY-163909 hydrochloride is a potent 5-hydroxytryptamine receptor 2C (5-HT2C) agonist with an EC50 of 8 nM and a maximum efficacy of 90%, while displaying minimal activity at 5-HT2A receptors. Its selectivity is further demonstrated by Ki values of 10.5 nM for 5-HT2C, alongside higher Ki values for 5-HT2A (212 nM), 5-HT7 (343 nM), and 5-HT2B (485 nM), and it lacks significant activity at various other receptors.

分子量

250.77

Formula

C14H19ClN2

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料

WAY 163909 hydrochloride 相关分类

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
WAY 163909 hydrochloride
目录号:
HY-15401A
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