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  4. Wy-45494 (hydrochloride) (Standard)

Wy-45494 (hydrochloride) (Standard)  (Synonyms: 盐酸文拉法辛EP杂质D (Standard)；1-[1-(4-甲氧基苯基)-2-(甲基氨基)乙基]环己醇盐酸盐 (Standard))

目录号: HY-131527R 纯度: ≥98%
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Wy-45494 (hydrochloride) (Standard)是 Wy-45494 (hydrochloride) 的分析标准品。本产品用于研究及分析应用。Wy-45494 hydrochloride (N-Desmethyl Venlafaxine hydrochloride; Wy 45494) 是选择性去甲肾上腺素和血清素再摄取抑制剂 (SNRI) 文拉法辛的次要活性代谢物。它由文拉法辛通过细胞色素 P450 (CYP) 异构体 CYP3A4.2 形成。Wy-45494 hydrochlor

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Wy-45494 (hydrochloride) (Standard) Chemical Structure

Wy-45494 (hydrochloride) (Standard) Chemical Structure

CAS No. : 93413-90-2

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生物活性

Wy-45494 (hydrochloride) (Standard) is the analytical standard of Wy-45494 (hydrochloride). This product is intended for research and analytical applications. Wy-45494 hydrochloride (N-Desmethyl Venlafaxine hydrochloride; Wy 45494) is a minor active metabolite of the selective norepinephrine and serotonin reuptake inhibitor (SNRI) venlafaxine. It is formed from venlafaxine via the cytochrome P450 (CYP) isomer CYP3A4.2. Wy-45494 hydrochloride inhibits norepinephrine and serotonin reuptake in rat synaptosomal preparations (IC50s of 4.7 and 1.6 μM, respectively). In vivo, Wy-45494 hydrochloride reversed reserpine-induced hypothermia in mice at a minimum effective dose (MED) of 10 mg/kg.

分子量

299.84

Formula

C16H26ClNO2
CAS 号
中文名称

盐酸文拉法辛EP杂质D (Standard)；1-[1-(4-甲氧基苯基)-2-(甲基氨基)乙基]环己醇盐酸盐 (Standard)
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料

Wy-45494 (hydrochloride) (Standard) 相关分类

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Keywords:

Wy-45494 (hydrochloride) (Standard)93413-90-2盐酸文拉法辛EP杂质D (Standard)1-[1-(4-甲氧基苯基)-2-(甲基氨基)乙基]环己醇盐酸盐 (Standard)OthersInhibitorinhibitorinhibit

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