2. Membrane Transporter/Ion Channel
  3. P-glycoprotein
  4. XR9051

XR9051 口服有效的、特异性的 P-糖蛋白介导的多药耐药特异性调节剂。

MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

XR9051 Chemical Structure

XR9051 Chemical Structure

CAS No. : 762219-35-2

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规格 是否有货
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Other Forms of XR9051:

XR9051 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

XR9051 is an orally active and specific modulator of P-glycoprotein-mediated multidrug resistance (MDR)[1].

体外研究
(In Vitro)

XR9051 is able to reverse resistance to a variety of cytotoxic drugs, including doxorubicin, etoposide and vincristine, which are associated with classical MDR[1].
XR9051 is highly active and gave at least a 15- to 20- fold decrease in the doxorubicin IC50, in the acquired resistance cell lines[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

XR9051 相关抗体:
体内研究
(In Vivo)

XR9051 (20-40 mg/kg, ip) shows significant modulatory activity in mice bearing MDR human ovarian (2780AD and CH1/DOXr) and SCLC (H69/LX) xenografts[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

642.74

Formula

C39H38N4O5
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

XR9051 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

XR9051762219-35-2XR 9051XR-9051P-glycoproteinP-gpPgpMultidrug resistance protein 1MDR1ATP-binding cassette sub-family B member 1ABCB1Cluster of differentiation 243CD243P-gtycoproteinmultidrug resistanceMDRovarian cancercolon carcinoma leukaemiaInhibitorinhibitorinhibit

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产品名称：
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目录号：
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