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  4. Zoledronate disodium

Zoledronate disodium  (Synonyms: CGP 42446 disodium; CGP42446A disodium; ZOL 446 disodium)

目录号: HY-13777C
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摩尔计算器

Zoledronate (CGP 42446) disodium 是一种强效双膦酸盐，可有效抑制破骨细胞生成、减少骨转换并稳定骨基质。Zoledronate disodium 通过抑制代谢活动和缓解骨痛，在抑制骨佩吉特病方面表现出显著效果。正在进行的 ZiPP 试验正在研究 Zoledronate disodium 在预防佩吉特病患者病情进展方面的潜力。Zoledronate disodium 在骨肉瘤中也表现出多种抗肿瘤作用，进一步凸显了其多功能抑制应用。

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Zoledronate disodium Chemical Structure

Zoledronate disodium Chemical Structure

CAS No. : 131654-46-1

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Zoledronate disodium 相关抗体

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  • 生物活性

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生物活性

Zoledronate (CGP 42446) disodium is a potent bisphosphonate that effectively inhibits osteoclastogenesis, reducing bone turnover and stabilizing the bone matrix. Zoledronate disodium has demonstrated notable effectiveness in managing Paget's disease of bone by suppressing metabolic activity and alleviating bone pain. Zoledronate disodium is being investigated in the ongoing ZiPP trial for its potential to prevent disease progression in patients with Paget's disease. Zoledronate disodium also exhibits diverse anti-tumor effects in osteosarcoma, further highlighting its multifunctional therapeutic applications.

分子量

316.05

Formula

C5H8N2Na2O7P2
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Zoledronate disodium 相关分类

  • 摩尔计算器

  • 稀释计算器

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  • Do most proteins show cross-species activity?

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Keywords:

Zoledronate disodium131654-46-1CGP 42446 disodiumCGP42446A disodiumZOL 446 disodiumOthersInhibitorinhibitorinhibit

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