2. Neuronal Signaling Stem Cell/Wnt
  3. γ-secretase Amyloid-β
  4. γ-Secretase modulator 12

γ-Secretase modulator 12 (Compound 1a) 是一种 γ-secretase 调节剂，可选择性降低淀粉样蛋白-β42 (Aβ42) 水平 (IC50 为 0.39 µM)。γ-Secretase modulator 12 可用于阿尔茨海默病研究。γ-Secretase modulator 12 在小鼠中具有良好的脑/血浆比 (Kp, brain = 0.72)。

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γ-Secretase modulator 12 Chemical Structure

γ-Secretase modulator 12 Chemical Structure

CAS No. : 2204249-82-9

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γ-Secretase modulator 12 相关抗体

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  • 生物活性

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生物活性

γ-Secretase modulator 12 (Compound 1a) is a γ-secretase modulator that can selectively decrease amyloid-β42 (Aβ42) levels (IC50 of 0.39 µM). γ-Secretase modulator 12 can be used for Alzheimer’s disease research. γ-Secretase modulator 12 has a good brain/plasma ratio (Kp, brain = 0.72) in mice[1].

分子量

397.47

Formula

C25H23N3O2
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

γ-Secretase modulator 12 相关分类

  • 摩尔计算器

  • 稀释计算器

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  • Do most proteins show cross-species activity?

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Keywords:

γ-Secretase modulator 122204249-82-9γ-secretaseAmyloid-βGamma secretaseβ-amyloid peptideAβAbetaγ-secretase modulatorAlzheimer’s diseaseamyloid-β42Inhibitorinhibitorinhibit

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