2. Metabolic Enzyme/Protease Apoptosis
  3. Phosphatase Apoptosis
  4. 1,2-Dipalmitoleoyl-sn-glycero-3-phosphoethanolamine

1,2-Dipalmitoleoyl-sn-glycero-3-phosphoethanolamine  (Synonyms: 16:1 PE)

目录号: HY-157673
产品使用指南 技术支持

1,2-Dipalmitoleoyl-sn-glycero-3-phosphoethanolamine (16:1 PE) 是一种磷脂酰乙醇胺，可增强恶性胸膜间皮瘤细胞中的 PP2A 和 PTP1B 活性。1,2-Dipalmitoleoyl-sn-glycero-3-phosphoethanolamine 诱导 NCI-H28 恶性胸膜间皮瘤细胞凋亡 (apoptosis)。

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1,2-Dipalmitoleoyl-sn-glycero-3-phosphoethanolamine Chemical Structure

1,2-Dipalmitoleoyl-sn-glycero-3-phosphoethanolamine Chemical Structure

CAS No. : 61599-23-3

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1,2-Dipalmitoleoyl-sn-glycero-3-phosphoethanolamine 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

1,2-Dipalmitoleoyl-sn-glycero-3-phosphoethanolamine (16:1 PE) is a phosphatidylethanolamine that can enhance PP2A and PTP1B activities in malignant pleural mesothelioma cells. 1,2-Dipalmitoleoyl-sn-glycero-3-phosphoethanolamine induces apoptosis of NCI-H28 malignant pleural mesothelioma cells[1].

体外研究
(In Vitro)

1,2-Dipalmitoleoyl-sn-glycero-3-phosphoethanolamine (DPPE; 1-100 μM; 24-48 hours) 以浓度依赖性方式（1-100 μM）降低 NCI-H28 细胞活力，但对 Met5A（非恶性间皮细胞）没有影响细胞[1]。
1,2-Dipalmitoleoyl-sn-glycero-3-phosphoethanolamine (DPPE; 100 μM; 10-60 minutes) 倾向于减弱 ERK1/ERK2 的活性[1]。
1,2-Dipalmitoleoyl-sn-glycero-3-phosphoethanolamine (DPPE; 30-100 μM; 48 hours) 显著增加 TUNEL 阳性 NCI-H28 细胞，表明细胞凋亡，对 Met5A 的影响最小[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

1,2-Dipalmitoleoyl-sn-glycero-3-phosphoethanolamine 相关抗体:

Cell Viability Assay[1]

Cell Line: NCI-H28 (Malignant pleural mesothelioma)
Concentration: 1 μM, 10 μM, 100 μM
Incubation Time: 24 hours, 48 hours
Result: Reduced NCI-H28 cell viability in a concentration-dependent manner.

Western Blot Analysis[1]

Cell Line: NCI-H28 (Malignant pleural mesothelioma)
Concentration: 100 μM
Incubation Time: 10 minutes, 30 minutes, 60 minutes
Result: Attenuated phosphorylation of ERK1/2 in NCI-H28 cells.

Apoptosis Analysis[1]

Cell Line: NCI-H28 (Malignant pleural mesothelioma)
Concentration: 30 and 100 μM
Incubation Time: 48 hours
Result: Induced apoptosis in NCI-H28 cells.
分子量

687.93

Formula

C37H70NO8P
CAS 号
中文名称

1,2-二棕榈油酰基-sn-甘油-3-磷酸乙醇胺
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

1,2-Dipalmitoleoyl-sn-glycero-3-phosphoethanolamine 相关分类

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  • Do most proteins show cross-species activity?

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Keywords:

1,2-Dipalmitoleoyl-sn-glycero-3-phosphoethanolamine61599-23-316:1 PE1,2-二棕榈油酰基-sn-甘油-3-磷酸乙醇胺PhosphataseApoptosisInhibitorinhibitorinhibit

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