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  5. 1-Acetyl-β-carboline

1-Acetyl-β-carboline  (Synonyms: 1-(9H-pyrido[3,4-b]indol-1-yl)ethanone)

目录号: HY-W060074 纯度: 97.04%
COA 产品使用指南

摩尔计算器

1-Acetyl-β-carboline 是 Nonomuraea endophytica 的代谢产物。

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1-Acetyl-β-carboline Chemical Structure

1-Acetyl-β-carboline Chemical Structure

CAS No. : 50892-83-6

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规格 价格 是否有货 数量
1 mg ￥4800
In-stock
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1-Acetyl-β-carboline 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

1-Acetyl-β-carboline is metabolite of Nonomuraea endophytica[1].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
A549 GI50
> 40 μM
Compound: 41
Cytotoxicity activity against human A549 cells assessed as growth inhibition at 10 ug/ml after 72 hrs sulforhodamine B assay
Cytotoxicity activity against human A549 cells assessed as growth inhibition at 10 ug/ml after 72 hrs sulforhodamine B assay
[PMID: 21316977]
A549 IC50
> 50 μM
Compound: 7
Cytotoxicity against human A549 cells after 48 hrs by MTT assay
Cytotoxicity against human A549 cells after 48 hrs by MTT assay
[PMID: 21977916]
DU-145 GI50
> 40 μM
Compound: 41
Cytotoxicity activity against human DU145 cells assessed as growth inhibition at 10 ug/ml after 72 hrs sulforhodamine B assay
Cytotoxicity activity against human DU145 cells assessed as growth inhibition at 10 ug/ml after 72 hrs sulforhodamine B assay
[PMID: 21316977]
DU-145 IC50
> 50 μM
Compound: 7
Cytotoxicity against human DU145 cells after 48 hrs by MTT assay
Cytotoxicity against human DU145 cells after 48 hrs by MTT assay
[PMID: 21977916]
HeLa IC50
> 50 μM
Compound: 7
Cytotoxicity against human HeLa cells after 48 hrs by MTT assay
Cytotoxicity against human HeLa cells after 48 hrs by MTT assay
[PMID: 21977916]
HT-22 IC50
> 100 μM
Compound: 31
Cytotoxicity against mouse HT-22 cells assessed as reduction in cell viability incubated for 48 hrs by MTS assay
Cytotoxicity against mouse HT-22 cells assessed as reduction in cell viability incubated for 48 hrs by MTS assay
[PMID: 36876904]
KB GI50
> 40 μM
Compound: 41
Cytotoxicity activity against human KB cells assessed as growth inhibition at 10 ug/ml after 72 hrs sulforhodamine B assay
Cytotoxicity activity against human KB cells assessed as growth inhibition at 10 ug/ml after 72 hrs sulforhodamine B assay
[PMID: 21316977]
MCF7 IC50
> 50 μM
Compound: 7
Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay
Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay
[PMID: 21977916]
MDA-MB-231 IC50
> 50 μM
Compound: 7
Cytotoxicity against human MDA-MB-231 cells after 48 hrs by MTT assay
Cytotoxicity against human MDA-MB-231 cells after 48 hrs by MTT assay
[PMID: 21977916]
NCI-H460 IC50
> 50 μM
Compound: 7
Cytotoxicity against human NCI-H460 cells after 48 hrs by MTT assay
Cytotoxicity against human NCI-H460 cells after 48 hrs by MTT assay
[PMID: 21977916]
Neutrophil IC50
5.03 μM
Compound: 41
Antiinflammatory activity against human neutrophil assessed as inhibition of N-formyl-l-methionyl phenylalanine/cytochalasin B-induced superoxide anion generation by spectrophotometry
Antiinflammatory activity against human neutrophil assessed as inhibition of N-formyl-l-methionyl phenylalanine/cytochalasin B-induced superoxide anion generation by spectrophotometry
[PMID: 21316977]
SMMC-7721 IC50
> 50 μM
Compound: 7
Cytotoxicity against human SMMC7721 cells after 48 hrs by MTT assay
Cytotoxicity against human SMMC7721 cells after 48 hrs by MTT assay
[PMID: 21977916]
SW1990 IC50
> 50 μM
Compound: 7
Cytotoxicity against human SW1990 cells after 48 hrs by MTT assay
Cytotoxicity against human SW1990 cells after 48 hrs by MTT assay
[PMID: 21977916]
分子量

210.23

Formula

C13H10N2O
CAS 号
性状

固体

颜色

Light yellow to yellow

中文名称

1-Acetyl一carboline
结构分类
初始来源

Nonomuraea endophytica
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
溶解性数据
细胞实验： 

DMSO 中的溶解度 : 50 mg/mL (237.83 mM; 超声助溶; 吸湿的 DMSO 对产品的溶解度有显著影响，请使用新开封的 DMSO)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 4.7567 mL 23.7835 mL 47.5670 mL
5 mM 0.9513 mL 4.7567 mL 9.5134 mL
查看完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month。-80°C储存时，请在6个月内使用，-20°C储存时，请在1个月内使用。

  • 摩尔计算器

  • 稀释计算器

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量
=
浓度
×
体积
×
分子量 *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start)

C1

×
体积 (start)

V1

=
浓度 (final)

C2

×
体积 (final)

V2

动物溶解方案计算器
请输入动物实验的基本信息：

给药剂量

mg/kg

动物的平均体重

g

每只动物的给药体积

μL

动物数量

只
由于实验过程有损耗，建议您多配一只动物的量
计算结果
工作液所需浓度 : mg/mL
纯度 & 产品资料
参考文献

1-Acetyl-β-carboline 相关分类

完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month。-80°C储存时，请在6个月内使用，-20°C储存时，请在1个月内使用。

可选溶剂 浓度 溶剂体积 质量 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 4.7567 mL 23.7835 mL 47.5670 mL 118.9174 mL
5 mM 0.9513 mL 4.7567 mL 9.5134 mL 23.7835 mL
10 mM 0.4757 mL 2.3783 mL 4.7567 mL 11.8917 mL
15 mM 0.3171 mL 1.5856 mL 3.1711 mL 7.9278 mL
20 mM 0.2378 mL 1.1892 mL 2.3783 mL 5.9459 mL
25 mM 0.1903 mL 0.9513 mL 1.9027 mL 4.7567 mL
30 mM 0.1586 mL 0.7928 mL 1.5856 mL 3.9639 mL
40 mM 0.1189 mL 0.5946 mL 1.1892 mL 2.9729 mL
50 mM 0.0951 mL 0.4757 mL 0.9513 mL 2.3783 mL
60 mM 0.0793 mL 0.3964 mL 0.7928 mL 1.9820 mL
80 mM 0.0595 mL 0.2973 mL 0.5946 mL 1.4865 mL
100 mM 0.0476 mL 0.2378 mL 0.4757 mL 1.1892 mL
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

1-Acetyl-β-carboline50892-83-61-(9H-pyrido[3,4-b]indol-1-yl)ethanone1-Acetyl一carbolineOthersInhibitorinhibitorinhibit

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