1. Membrane Transporter/Ion Channel
  2. P-glycoprotein
  3. 11α-O-Benzoyl-12β-O-acetyltenacigenin B

11α-O-Benzoyl-12β-O-acetyltenacigenin B 

目录号: HY-N13157
产品使用指南

11α-O-Benzoyl-12β-O-acetyltenacigenin B 是一种源自 Marsdenia tenacissima 的 P-糖蛋白 (Pgp) 抑制剂,属于Tenacigenin B (HY-N1168) 衍生物。11α-O-Benzoyl-12β-O-acetyltenacigenin B 可以在 HepG2/Dox 细胞抑制 P-糖蛋白 (Pgp) 过表达导致的多药耐药性 (MDR),有望用于癌症领域的研究。

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11α-O-Benzoyl-12β-O-acetyltenacigenin B Chemical Structure

11α-O-Benzoyl-12β-O-acetyltenacigenin B Chemical Structure

CAS No. : 154022-52-3

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  • 生物活性

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生物活性

11α-O-Benzoyl-12β-O-acetyltenacigenin B is a P-glycoprotein (Pgp) inhibitor derived from Marsdenia tenacissima and belongs to the Tenacigenin B (HY-N1168) derivatives. 11α-O-Benzoyl-12β-O-acetyltenacigenin B can inhibit multidrug resistance (MDR) caused by P-glycoprotein (Pgp) overexpression in HepG2/Dox cells and holds potential for research in the field of cancer[1].

分子量

510.62

Formula

C30H38O7

CAS 号
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

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参考文献
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产品名称:
11α-O-Benzoyl-12β-O-acetyltenacigenin B
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HY-N13157
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