2. Metabolic Enzyme/Protease
  3. 11β-HSD
  4. 11β-HSD2-IN-2

11β-HSD2-IN-2 (compound 3) 是 2 型 7β-羟基类固醇脱氢酶 (17β-HSD2) 的选择性抑制剂，IC50 为 300 nM。

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11β-HSD2-IN-2 Chemical Structure

11β-HSD2-IN-2 Chemical Structure

CAS No. : 1834601-37-4

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11β-HSD2-IN-2 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

11β-HSD2-IN-2 (compound 3) is a selective inhibitor for 17β-hydroxysteroid dehydrogenase type 2 (17β-HSD2) with an IC50 of 300 nM[1].

IC50 & Target

IC50: 300 nM (17β-HSD2 Inhibitor); 16100 nM (17β-HSD1 Inhibitor)
体外研究
(In Vitro)

11β-HSD2-IN-2 (0-100 μM) 在 HEK293 细胞中表现出中度的细胞毒性，LD50 大约为 25 μM[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

11β-HSD2-IN-2 相关抗体:

Cell Viability Assay[1]

Cell Line: HEK293
Concentration: 0-100 μM
Incubation Time: 66 h
Result: Decreased cell viability in a dose-dependent manner.
分子量

331.41

Formula

C22H21NO2
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

11β-HSD2-IN-2 相关分类

  • 摩尔计算器

  • 稀释计算器

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

11β-HSD2-IN-21834601-37-411β-HSD11beta-HSD11β-hydroxysteroid dehydrogenases11 beta-hydroxysteroid dehydrogenaseHEK293osteoporosisInhibitorinhibitorinhibit

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