2. JAK/STAT Signaling Stem Cell/Wnt
  3. STAT
  4. 15(R)-Lipoxin A4

15(R)-Lipoxin A4  (Synonyms: 15-epi-LXA4)

目录号: HY-113509B
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摩尔计算器

15(R)-Lipoxin A4 (15-epi-LXA4) 是一种 STAT-6 激活剂，是脂质衍生的脂氧素类型的解决介质 (SPMs)，具有促进炎症解决和免疫细胞功能调节的作用。15(R)-Lipoxin A4 可改善微胶质细胞的吞噬功能，具有抗炎活性。15(R)-Lipoxin A4 阿尔茨海默病 (AD) 的小鼠模型中可改善 AD 样病理。15(R)-Lipoxin A4 有望用于炎症及神经疾病研究。

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15(R)-Lipoxin A4 Chemical Structure

15(R)-Lipoxin A4 Chemical Structure

CAS No. : 171030-11-8

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Other Forms of 15(R)-Lipoxin A4:

15(R)-Lipoxin A4 相关抗体

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STAT3 STAT5 STAT6 STAT1

  • 生物活性

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生物活性

15(R)-Lipoxin A4 (15-epi-LXA4) is a STAT-6 activator and a lipid-derived lipoxin-type specialized pro-resolving mediator (SPM) that plays a role in promoting inflammation resolution and regulating immune cell function. 15(R)-Lipoxin A4 can improve the phagocytic function of microglia and exhibits anti-inflammatory activity. In Alzheimer's disease (AD) mouse models, 15(R)-Lipoxin A4 improves AD-like pathology. 15(R)-Lipoxin A4 holds potential for use in inflammation and neurodegenerative disease research[1].

IC50 & Target

STAT6

 

分子量

352.47

Formula

C20H32O5
CAS 号
结构分类
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

15(R)-Lipoxin A4 相关分类

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  • Do most proteins show cross-species activity?

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Keywords:

15(R)-Lipoxin A4171030-11-815-epi-LXA4STATInhibitorinhibitorinhibit

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