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  3. 16-epi-Latrunculin B

16-epi-latrunculin B 是一种抗癌剂,可以抑制 HeLa 细胞的生长,IC50 值为 3.9 uM。 16-epi-latrunculin B 具有抗病毒作用,对 HSV-1 的 ED50 值为 1 µg/mL.

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16-epi-Latrunculin B Chemical Structure

16-epi-Latrunculin B Chemical Structure

CAS No. : 444911-05-1

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生物活性

16-epi-latrunculin B is anticancer agent, which can inhibit the growth of HeLa cells with IC50 value of 3.9 uM[1]. 16-epi-latrunculin B has antiviral activity against HSV-1 (ED50 of 1 µg/mL)[2].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
HCT-116 IC50
38 μM
Compound: 3
Cytotoxicity against human HCT116 cells after 3 days by trypan blue assay
Cytotoxicity against human HCT116 cells after 3 days by trypan blue assay
[PMID: 18942825]
MDA-MB-435 IC50
17 μM
Compound: 3
Cytotoxicity against human MDA-MB-435 cells 48 hrs by SRB assay
Cytotoxicity against human MDA-MB-435 cells 48 hrs by SRB assay
[PMID: 18942825]
分子量

395.51

Formula

C20H29NO5S

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

16-epi-Latrunculin B 相关分类

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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16-epi-Latrunculin B
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