1. Others Neuronal Signaling Membrane Transporter/Ion Channel
  2. TRP Channel Isotope-Labeled Compounds
  3. 17(R)-Resolvin D1-d5

17(R)-Resolvin D1-d5  (Synonyms: 17(R)-RvD1-d5; AT-RvD1-d5)

目录号: HY-125527AS
产品使用指南

17(R)-Resolvin D1-d5 (17(R)-RvD1-d5) 是氘代标记的 17(R)-Resolvin D1。17R-Resolvin D1 (17R-RvD1; AT-RvD1) 是阿司匹林触发的 Resolvin D1 的差向异构体,在小鼠和人 PMNS 细胞中都表现出抗炎活性。17R-Resolvin D1 特异性抑制 TRPV3IC50 为 398 nM,并表现出外周镇痛作用。

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17(R)-Resolvin D1-d<sub>5</sub> Chemical Structure

17(R)-Resolvin D1-d5 Chemical Structure

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生物活性

17(R)-Resolvin D1-d5 (17(R)-RvD1-d5) is deuterium labeled 17(R)-Resolvin D1. 17R-Resolvin D1 (17R-RvD1; AT-RvD1) is an aspirin-triggered epimer of Resolvin D1, which exhibits anti-inflammatory activity in mice and human PMNs cells[1]. 17R-Resolvin D1 specificially inhibits TRPV3 with an IC50 of 398 nM and exhibits peripheral anti-nociceptive efficacy[2].

分子量

381.52

Formula

C22H27D5O5

非标记 CAS

528583-91-7

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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17(R)-Resolvin D1-d5
目录号:
HY-125527AS
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