1. Anti-infection
  2. Enterovirus
  3. 2-Hydroxytetradecanoic acid

2-Hydroxytetradecanoic acid  (Synonyms: 2-羟基十四碳酸)

目录号: HY-W012017 纯度: 99.91%
COA 产品使用指南 技术支持

2-Hydroxytetradecanoic Acid 是一种羟基脂肪酸,可抑制肠道病毒 (enterovirus) 衣壳蛋白 VP4 和 VP2 之间的裂解。2-Hydroxytetradecanoic Acid 有抗病毒活性。

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2-Hydroxytetradecanoic acid Chemical Structure

2-Hydroxytetradecanoic acid Chemical Structure

CAS No. : 2507-55-3

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规格 价格 是否有货 数量
10 mM * 1 mL in DMSO ¥715
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1 mg ¥266
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5 mg ¥550
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10 mg ¥850
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25 mg ¥1450
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50 mg ¥2200
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100 mg ¥3320
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200 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

2-Hydroxytetradecanoic acid is a hydroxy fatty acid that inhibits cleavage between the enterovirus capsid proteins VP4 and VP2. 2-Hydroxytetradecanoic Acid has anti-virus activity[1].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
CHO EC50
3.86 μM
Compound: 22
Agonist activity at recombinant human GPR84 expressed in CHO cell membranes co-expressing beta-arrestin2 assessed as inhibition of forskolin-stimulated [3H]cAMP accumulation preincubated for 5 mins followed by forskolin stimulation and measured after 15 m
Agonist activity at recombinant human GPR84 expressed in CHO cell membranes co-expressing beta-arrestin2 assessed as inhibition of forskolin-stimulated [3H]cAMP accumulation preincubated for 5 mins followed by forskolin stimulation and measured after 15 m
[PMID: 31721581]
CHO EC50
4.36 μM
Compound: 22
Agonist activity at recombinant human GPR84 expressed in CHO cell membranes co-expressing beta-arrestin2 assessed as beta-arrestin 2 recruitment measured after 90 mins by beta-galactosidase based PathHunter assay
Agonist activity at recombinant human GPR84 expressed in CHO cell membranes co-expressing beta-arrestin2 assessed as beta-arrestin 2 recruitment measured after 90 mins by beta-galactosidase based PathHunter assay
[PMID: 31721581]
分子量

244.37

Formula

C14H28O3

CAS 号
性状

固体

颜色

White to off-white

中文名称

2-羟基十四碳酸

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
溶解性数据
细胞实验: 

DMSO 中的溶解度 : 175 mg/mL (716.13 mM; 超声助溶; 吸湿的 DMSO 对产品的溶解度有显著影响,请使用新开封的 DMSO)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 4.0922 mL 20.4608 mL 40.9216 mL
5 mM 0.8184 mL 4.0922 mL 8.1843 mL
查看完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80°C, 6 months; -20°C, 1 month。-80°C储存时,请在6个月内使用,-20°C储存时,请在1个月内使用。

  • 摩尔计算器

  • 稀释计算器

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量
=
浓度
×
体积
×
分子量 *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start)

C1

×
体积 (start)

V1

=
浓度 (final)

C2

×
体积 (final)

V2

动物溶解方案计算器
请输入动物实验的基本信息:

给药剂量

mg/kg

动物的平均体重

g

每只动物的给药体积

μL

动物数量

由于实验过程有损耗,建议您多配一只动物的量
计算结果
工作液所需浓度 : mg/mL
纯度 & 产品资料

纯度: 99.91%

参考文献

2-Hydroxytetradecanoic acid 相关分类

完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80°C, 6 months; -20°C, 1 month。-80°C储存时,请在6个月内使用,-20°C储存时,请在1个月内使用。

可选溶剂 浓度 溶剂体积 质量 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 4.0922 mL 20.4608 mL 40.9216 mL 102.3039 mL
5 mM 0.8184 mL 4.0922 mL 8.1843 mL 20.4608 mL
10 mM 0.4092 mL 2.0461 mL 4.0922 mL 10.2304 mL
15 mM 0.2728 mL 1.3641 mL 2.7281 mL 6.8203 mL
20 mM 0.2046 mL 1.0230 mL 2.0461 mL 5.1152 mL
25 mM 0.1637 mL 0.8184 mL 1.6369 mL 4.0922 mL
30 mM 0.1364 mL 0.6820 mL 1.3641 mL 3.4101 mL
40 mM 0.1023 mL 0.5115 mL 1.0230 mL 2.5576 mL
50 mM 0.0818 mL 0.4092 mL 0.8184 mL 2.0461 mL
60 mM 0.0682 mL 0.3410 mL 0.6820 mL 1.7051 mL
80 mM 0.0512 mL 0.2558 mL 0.5115 mL 1.2788 mL
100 mM 0.0409 mL 0.2046 mL 0.4092 mL 1.0230 mL
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
2-Hydroxytetradecanoic acid
目录号:
HY-W012017
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